As we age, shifting hormone levels can change our skin leading to dryness, fine lines, and loss of elasticity.
At HerMD, we understand these changes aren’t just cosmetic—they can affect how you feel in your own skin. That’s why we offer Estrogen Face Cream, available through HerMD Pharmacy.
What is Estriol?
You may know the term estradiol, but have you heard of estriol?
Estriol is one of the “big three” primary estrogens produced in the body. It’s considered a gentle form of estrogen because it doesn’t stimulate tissues as potently as estradiol. This makes it ideal for use on sensitive areas like the face and neck, where it can improve local tissue health without affecting the rest of the body.
In contrast, estradiol is a stronger estrogen and is commonly used in systemic menopausal hormone therapy.
What the Research Says
Topical estrogen has been shown to offer several benefits for aging skin.
In a small study of 59 women, using an estrogen-containing facial cream for six months improved skin elasticity, firmness, and moisture, while wrinkle depth and pore size decreased by 61 to 100%.
In a recent randomized clinical trial investigating the effects of estrogen-containing facial creams, after 12 weeks, individuals who applied an estriol-containing product saw significant improvements in skin elasticity, hydration, and texture, with the skin appearing firmer, plumper, and smoother.
See the Difference
The contrasting pictures of the identical twins shown below highlight the impact of estrogen-containing therapy on skin health.
Twin B (right) used hormone therapy for 22 more years than her sister (left) and appears noticeably younger, demonstrating how this hormone helps keep skin firm, hydrated, and youthful.
Surg. 2009;123(4):1321-1330. doi:10.1097/PRS.0b013e31819f56fd
Key Benefits of Estriol at a Glance:
- Targets skin changes from menopause and perimenopause by providing localized estrogen support.
- Improves hydration and elasticity so skin feels smoother and looks more radiant.
- Supports collagen production to help skin appear firmer and regain volume.
- Reduces the appearance of fine lines and wrinkles, helping skin appear youthful and revitalized.
- Custom-compounded for you through our trusted partner pharmacy, Curexa—ensuring the highest quality and consistency.
Why patients love it:
- Backed by clinical evidence
- Formulated for your unique needs
- Delivered without extra pharmacy trips
How to get it:
- Schedule an appointment with your HerMD provider to see if Estriol Face Cream is right for you.
- Your prescription is sent directly to Curexa.
- We process payment at HerMD.
- Curexa ships the cream right to your door.
If you’d like to learn whether Estriol Face Cream is right for you, schedule an appointment today. Because at HerMD, we believe skincare should do more than sit on the surface—it should work in harmony with your health.
Disclaimer: HerMD offers access to compounded medications that have not been approved by the FDA. The FDA does not evaluate the safety or effectiveness of compounded medications. These formulations are prescribed based on science, real-world outcomes, and clinical expertise. In close collaboration with our pharmacy partner, licensed pharmacists prepare every medication following the highest quality standards and rigorous regulatory protocols to guarantee safety and consistency. To access treatment, patients must schedule an appointment with a licensed HerMD provider, who will determine if a prescription is appropriate based on individual needs. The actual cost to the patient will vary based on the prescribed medication.