Testosterone plays an important role in women’s health — especially during menopause.
As women age, their testosterone levels gradually decline, and by menopause, they can be about 50% lower than levels in early adulthood. This decline can lead to symptoms such as diminished sexual desire, decreased muscle strength, mood changes, and difficulties with concentration or memory.
Low-dose testosterone therapy for women is becoming increasingly recognized as a treatment option to help manage symptoms related to declining testosterone levels. Although no testosterone therapies are currently FDA-approved specifically for women in the United States, growing clinical evidence supports its use under the careful guidance and monitoring of a healthcare provider. However, long-term safety data are still limited, and ongoing research is needed to understand better the full risk–benefit profile of testosterone use in women.
Potential Benefits of Testosterone Therapy
Evidence* suggests that testosterone therapy use in women may help support:
Sexual function
- Increased sexual desire
- Enhanced sexual arousal
- Improved orgasmic function
- Greater sexual pleasure and responsiveness
- Reduction in sexual concerns and distress
Energy & Vitality
Mood & Confidence
Bone & Brain Health
Muscle Tone & Strength
Breast Health
Testosterone may help protect breast tissue and reduce the risk of changes linked to other hormone treatments.
How is Testosterone Prescribed at HerMD?
Testosterone is prescribed through HerMD Pharmacy and administered using the Topi-CLICK® system, which delivers an easy, precise dose with just one click applied to the inner thigh or back of the calf.
HerMD offers access to compounded medications that have not been approved by the FDA. The FDA does not evaluate the safety or effectiveness of compounded medications. These formulations are prescribed based on science, real-world outcomes, and clinical expertise. In close collaboration with our pharmacy partner, licensed pharmacists prepare every medication following the highest quality standards and rigorous regulatory protocols to guarantee safety and consistency.
To access treatment, patients must schedule an appointment with a licensed HerMD provider, who will determine if a prescription is appropriate based on individual needs. The actual cost to the patient will vary based on the prescribed medication.
*Sources:
Davis SR, Baber R, Panay N, et al. Global Consensus Position Statement on the Use of Testosterone Therapy for Women. Climacteric. 2019;22(5):429-434. doi:10.1080/13697137.2019.1637079
Glynne S, Kamal A, Kamel AM, Reisel D, Newson L. Effect of transdermal testosterone therapy on mood and cognitive symptoms in peri- and postmenopausal women: a pilot study. Arch Womens Ment Health. 2025;28(3):541-550. doi:10.1007/s00737-024-01513-6
Elraiyah T, Sonbol MB, Wang Z, et al. Clinical review: The benefits and harms of systemic testosterone therapy in postmenopausal women with normal adrenal function: a systematic review and meta-analysis. J Clin Endocrinol Metab. 2014;99(10):3543-3550. doi:10.1210/jc.2014-2262
Yang J, Kong G, Yao X, Zhu Z. Association between Serum Total Testosterone Level and Bone Mineral Density in Middle-Aged Postmenopausal Women. Int J Endocrinol. 2022;2022:4228740. Published 2022 Aug 17. doi:10.1155/2022/4228740
Davison SL, Bell RJ, Gavrilescu M, et al. Testosterone improves verbal learning and memory in postmenopausal women: Results from a pilot study. Maturitas. 2011;70(3):307-311. doi:10.1016/j.maturitas.2011.08.006
Hofling M, Hirschberg AL, Skoog L, Tani E, Hägerström T, von Schoultz B. Testosterone inhibits estrogen/progestogen-induced breast cell proliferation in postmenopausal women. Menopause. 2007;14(2):183-190. doi:10.1097/01.gme.0000232033.92411.51